Immune receptors and cytokines and their effect on the immune status of leishmaniasis patients

Abstract

The study samples were collected from Samarra General Hospital and external dermatology clinics. The number of studied samples was 60 samples infected with cutaneous leishmaniasis after clinical confirmation by a specialist physician and 30 samples from healthy individuals. The study period was from October 2022 to March 2023 and the results were as follows: For tumor necrosis factor alpha, the results in patients were (1.1923 + 0.0713) pg/ml, which is high when compared to healthy people (0.4831 + 0.0528) pg/ml. As for the level of interleukin-2, the results in patients were (0.908 + 0.258) pg/ml compared to healthy people (0.4259 + 0.0554) pg/ml. As for the levels of interleukin-4, the results in patients were (0.769 + 0.236) pg/ml compared to healthy people (0.5187 + 0.0950) pg/ml. As for the levels of interleukin-13, the results in patients were (1.132 + 0.173) pg/ml, while in people The healthy people had (0.4748 + 0.0776) pg/ml, while the results of Toll-2 receptors in the infected people were (0.700 + 0.184) pg/ml, which is a high percentage compared to healthy people (0.3660 + 0.0874) pg/ml. As for Toll-4 receptors, the results of the infected people were (0.960 + 0.226) pg/ml compared to healthy people (0.574 + 0.108) pg/ml.